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TANGO Tools for Analysis of Nuclear Genome Organization

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Author(s): 
Jean Ollion, Julien Cochennec, Christophe Escudé, François Loll, Thomas Boudier
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About

TANGO software is an open-source software for Analysis of Nuclear Genome Organization. It is composed of an ImageJ plugin for batch processing and analysis, and a R package for statistical analysis.

Reference: [1]

Some key features

  • Image import uses bioimage formats.
  • Construction of workflow in GUI by choosing filters / segmentation strategy for
    • Prefiltering
    • Segmentation
    • Postfiltering
  • Isolated nuclei could individually be inspected, deleted from list and subjected for detailed analysis.
  • Uses MCIB3D library as backend.
  • Basic usage is to segment nucleus, crop them to single nucleus objects, segment substructures within objects and measure their properties.
  • Optionally R can be connected to do detailed analysis of results.
  • Uses MongoDB to manage huge data set.

References